Quarterback Alex Smith threw a six-yard touchdown pass to tight end Delanie Walker with 1:51 remaining as the San Francisco 49ers came from behind to knock off the previously undefeated Detroit Lions 25-19 in Sunday National Football League action. Frank Gore carried the ball 15 times for 141 yards (including runs of 47 and 55 yards) and a touchdown (1 yard). The defeat ended the Lions' regular-season winning streak at nine games dating back to last season. The Niners now hold a 2 and 1/2 game lead atop the NFC West Division. Both teams are now at 5-1.